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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLNS1A
All Species:
21.82
Human Site:
Y200
Identified Species:
34.29
UniProt:
P54105
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54105
NP_001284.1
237
26215
Y200
S
Q
S
V
S
S
Q
Y
N
M
A
G
V
R
T
Chimpanzee
Pan troglodytes
XP_001175048
222
24569
G190
A
T
L
E
R
L
E
G
M
L
S
Q
S
V
S
Rhesus Macaque
Macaca mulatta
XP_001088333
203
22330
V171
S
Q
Y
N
M
A
G
V
R
T
E
D
S
I
R
Dog
Lupus familis
XP_535567
226
24585
V194
S
Q
Y
N
M
A
G
V
R
T
E
D
S
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61189
236
26003
Y199
S
Q
S
V
S
S
Q
Y
N
M
A
G
V
R
T
Rat
Rattus norvegicus
Q04753
236
26074
Y199
S
Q
S
V
S
S
Q
Y
N
M
A
G
V
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519221
278
30242
Y210
A
Q
S
E
G
S
R
Y
H
M
A
G
V
R
T
Chicken
Gallus gallus
XP_423253
238
26615
Y201
A
Q
S
V
S
S
Q
Y
N
M
A
G
V
R
T
Frog
Xenopus laevis
P54106
241
26428
H204
S
N
S
I
G
N
Q
H
T
M
A
G
V
R
T
Zebra Danio
Brachydanio rerio
NP_571499
249
27316
Y213
A
Q
S
V
A
Q
Q
Y
H
M
A
G
V
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611237
215
23724
E183
D
A
G
G
L
E
D
E
A
M
E
E
D
D
A
Honey Bee
Apis mellifera
XP_624081
207
23224
L175
A
G
D
A
P
Y
I
L
P
T
E
Q
I
G
T
Nematode Worm
Caenorhab. elegans
NP_001021287
205
22895
H173
F
T
A
D
N
I
D
H
M
Q
M
S
E
E
G
Sea Urchin
Strong. purpuratus
XP_001194575
165
18108
D133
E
E
E
G
G
E
E
D
P
E
I
G
I
E
L
Poplar Tree
Populus trichocarpa
XP_002318279
231
25740
H199
I
G
H
S
N
G
D
H
D
L
A
R
T
V
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
85.6
82.2
N.A.
90.3
90.3
N.A.
40.6
82.3
72.1
68.2
N.A.
20.2
40
29.9
24.4
Protein Similarity:
100
93.2
85.6
85.2
N.A.
94.9
94.9
N.A.
53.2
90.3
82.5
80.3
N.A.
37.5
56.5
45.5
40.9
P-Site Identity:
100
0
13.3
13.3
N.A.
100
100
N.A.
66.6
93.3
60
73.3
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
33.3
20
20
N.A.
100
100
N.A.
86.6
100
80
93.3
N.A.
6.6
20
20
26.6
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
7
7
7
7
14
0
0
7
0
54
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
7
0
0
20
7
7
0
0
14
7
7
0
% D
% Glu:
7
7
7
14
0
14
14
7
0
7
27
7
7
14
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
14
7
14
20
7
14
7
0
0
0
54
0
7
7
% G
% His:
0
0
7
0
0
0
0
20
14
0
0
0
0
0
0
% H
% Ile:
7
0
0
7
0
7
7
0
0
0
7
0
14
14
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
7
0
7
7
0
7
0
14
0
0
0
0
14
% L
% Met:
0
0
0
0
14
0
0
0
14
54
7
0
0
0
0
% M
% Asn:
0
7
0
14
14
7
0
0
27
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
7
0
0
0
14
0
0
0
0
0
0
% P
% Gln:
0
54
0
0
0
7
40
0
0
7
0
14
0
0
0
% Q
% Arg:
0
0
0
0
7
0
7
0
14
0
0
7
0
47
14
% R
% Ser:
40
0
47
7
27
34
0
0
0
0
7
7
20
0
7
% S
% Thr:
0
14
0
0
0
0
0
0
7
20
0
0
7
0
54
% T
% Val:
0
0
0
34
0
0
0
14
0
0
0
0
47
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
14
0
0
7
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _